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Avodart (Dutasteride) 0.5mg capsules

 
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0.5 mg
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Avodart, is a treatment for male pattern hair loss. Is is a potent 5-alpha reductase inhibitor, and effectively reduces the production of dihydrotestosterone (DHT). This is a hormone that plays a key role in hair follicle shrinkage and hair loss in men.

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Description

When testosterone is produced in your body, it is used for many purposes. Testosterone is a male sex hormone. In some cases, it will be converted into a hormone called dihydrotestosterone, or DHT. This compound has many uses in the body but has unfortunate side effects as well. 

When hair follicles are exposed to DHT, they shrink, getting less blood flow. This means they won’t produce as much hair, and eventually they will fall into a sort of stasis; after so long without proper blood flow, they will start to die off.

Avodart works by preventing testosterone from being converted to DHT, in turn improving blood flow which allows the hair follicles to regain their normal size. 

In some cases, Avodart can reactivate hair follicles which have been in stasis, but haven’t yet died off; this can look like hair regrowth, but Avodart cannot revive dead follicles. You are most likely to notice these follicles reawakening in the first 3 to 6 months of treatment - after that, the treatment will help you keep the hair you have.

Warnings

Avodart may not be suitable for all patients. Do not take this medication if you;

  • Are allergic to Avodart, including other 5-alpha reductase inhibitors or any of the listed ingredients
  • Have severe liver disease
  • Are under the age of 18

This medication is for men only. Do not take it if you are a woman or under the age of 18. Talk to your doctor before taking this medication if your partner is pregnant, breastfeeding or plans to become pregnant. 

Avodart can be absorbed through the skin; pregnant women, children  and adolescents should avoid handling leaking or damaged capsules.

Speak to your doctor before taking Dutasteride (Avodart) if you are taking any other medications. In particular, the following medications may interact with Avodart, and make you more likely to experience side effects.

  • Verapamil or diltiazem (to treat high blood pressure)
  • Ritonavir or indinavir (to treat HIV)
  • Itraconazole or ketoconazole (to treat fungal infections)
  • Nefazodone (to treat depression)
  • Alpha-blockers (for enlarged prostate, or high blood pressure)

Directions

Avodart Dosing: Take 1 capsule daily

Ingredients

Each capsule contains 0.5 mg of dutasteride dissolved in a mixture of mono-di-glycerides of caprylic/capric acid and butylated hydroxytoluene. The inactive excipients in the capsule shell are gelatin (from certified BSE-free bovine sources), glycerin, and ferric oxide (yellow).

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

  • Chest pain or discomfort
  • dilated neck veins
  • extreme fatigue
  • irregular breathing
  • irregular heartbeat
  • swelling of the face, fingers, feet, or lower legs
  • trouble breathing
  • weight gain

Incidence not known

  • Blistering, flaking, or peeling of the skin
  • cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives or welts, itching skin, rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • tightness in the chest
  • unusual tiredness or weakness

FAQs

Is Avodart similar to Propecia?

Avodart is similar to Finasteride (Propecia); both block the conversion of testosterone to DHT.  Avodart is clinically shown to be up to 20% more effective at doing this (see study here). Although they have the same mode of action, some studies have shown that Avodart may be more effective at preventing hair loss than Finasteride (Propecia). One study showed that 86% of men with an M-shaped hairline reported improvement after 36 months of treatment with Avodart, compared to 45% of men taking Finasteride (Propecia).

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